Rottiers, V., and Näär, A.M. (2012). MicroRNAs in metabolism and metabolic disorders. Nat Rev Mol Cell Biol 13, 239-250.

Rottiers, V., Najafi-Shoushtari, S.H., Kristo, F., Gurumurthy, S., Zhong, L., Li, Y., Cohen, D.E., Gerszten, R.E., Bardeesy, N., Mostoslavsky, R., et al. (2011). MicroRNAs in Metabolism and Metabolic Diseases. Cold Spring Harb Symp Quant Biol.

Walker, A.K., Jacobs, R.L., Watts, J.L., Rottiers, V., Jiang, K., Finnegan, D.M., Shioda, T., Hansen, M., Yang, F., Niebergall, L.J., et al. (2011). A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans. Cell 147, 840-852.

Näär, A.M. (2011). MiRs with a sweet tooth. Cell Metabolism 14, 149-150.

Mulligan, P., Yang, F., Di Stefano, L., Ji, J.Y., Ouyang, J., Nishikawa, J.L., Toiber, D., Kulkarni, M., Wang, Q., Najafi-Shoushtari, S.H., et al. (2011). A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Molecular Cell 42, 689-699.

Milbradt, A.G., Kulkarni, M., Yi, T., Takeuchi, K., Sun, Z.Y., Luna, R.E., Selenko, P., Näär, A.M., and Wagner, G. (2011). Structure of the VP16 transactivator target in the Mediator. Nat Struct Mol Biol 18, 410-415.

Di Stefano, L., Walker, J.A., Burgio, G., Corona, D.F., Mulligan, P., Näär, A.M., and Dyson, N.J. (2011). Functional antagonism between histone H3K4 demethylases in vivo. Genes & Development 25, 17-28.

Walker, A.K., Yang, F., Jiang, K., Ji, J.Y., Watts, J.L., Purushotham, A., Boss, O., Hirsch, M.L., Ribich, S., Smith, J.J., et al. (2010). Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes & Development 24, 1403-1417.

Najafi-Shoushtari, S.H., Kristo, F., Li, Y., Shioda, T., Cohen, D.E., Gerszten, R.E., and Näär, A.M. (2010). MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 328, 1566-1569.

Shahi, P., Gulshan, K., Näär, A.M., and Moye-Rowley, W.S. (2010). Differential roles of transcriptional mediator subunits in regulation of multidrug resistance gene expression in Saccharomyces cerevisiae. Mol Biol Cell 21, 2469-2482.

Näär, A.M., and Thakur, J.K. (2009). Nuclear receptor-like transcription factors in fungi. Genes & Development 23, 419-432.

Thakur, J.K., Arthanari, H., Yang, F., Chau, K.H., Wagner, G., and Näär, A.M. (2009). Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p. The Journal of Biological Chemistry 284, 4422-4428.

Morris, E.J., Ji, J.Y., Yang, F., Di Stefano, L., Herr, A., Moon, N.S., Kwon, E.J., Haigis, K.M., Näär, A.M., and Dyson, N.J. (2008). E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8. Nature 455, 552-556.

Thakur, J.K., Arthanari, H., Yang, F., Pan, S.J., Fan, X., Breger, J., Frueh, D.P., Gulshan, K., Li, D.K., Mylonakis, E., et al. (2008). A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature 452, 604-609.

Beyer, K.S., Beauchamp, R.L., Lee, M.F., Gusella, J.F., Näär, A.M., and Ramesh, V. (2007). Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation. The Journal of Biological Chemistry 282, 32152-32157.

Binne, U.K., Classon, M.K., Dick, F.A., Wei, W., Rape, M., Kaelin, W.G., Jr., Näär, A.M., and Dyson, N.J. (2007). Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nat Cell Biol 9, 225-232.

Yang, F., Vought, B.W., Satterlee, J.S., Walker, A.K., Jim Sun, Z.Y., Watts, J.L., DeBeaumont, R., Saito, R.M., Hyberts, S.G., Yang, S., et al. (2006). An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature 442, 700-704.

Baillat, D., Hakimi, M.A., Näär, A.M., Shilatifard, A., Cooch, N., and Shiekhattar, R. (2005). Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell 123, 265-276.

Bourbon, H.M., Aguilera, A., Ansari, A.Z., Asturias, F.J., Berk, A.J., Bjorklund, S., Blackwell, T.K., Borggrefe, T., Carey, M., Carlson, M., et al. (2004). A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell 14, 553-557.

Yang, F., DeBeaumont, R., Zhou, S., and Näär, A.M. (2004). The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator. Proc Natl Acad Sci U S A 101, 2339-2344.

Kato, Y., Habas, R., Katsuyama, Y., Näär, A.M., and He, X. (2002). A component of the ARC/Mediator complex required for TGF beta/Nodal signalling. Nature 418, 641-646.

Näär, A.M., Taatjes, D.J., Zhai, W., Nogales, E., and Tjian, R. (2002). Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes & Development 16, 1339-1344.

Taatjes, D.J., Näär, A.M., Andel, F., 3rd, Nogales, E., and Tjian, R. (2002). Structure, function, and activator-induced conformations of the CRSP coactivator. Science 295, 1058-1062.

Näär, A.M., Lemon, B.D., and Tjian, R. (2001). Transcriptional coactivator complexes. Annu Rev Biochem 70, 475-501.

Ross, J., Näär, A.M., Cam, H., Gregory, R., Dynlacht, B.D. (2001). Active repression and E2F inhibition by pRB are biochemically distinguishable. Genes & Development 15, 392-7.



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